Amygdala Insula Retraining in the Management of Perimenopause Symptoms
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexFemale
Age38-60
SponsorChronic Conditions Research Fund
About this trial
The goal of this study is to evaluate a neuroplasticity-based mind-body intervention, Amygdala and Insula Retraining (AIR), compared to a wait-list control in individuals experiencing perimenopausal symptoms.
Our research questions include:
Does AIR reduce overall perimenopausal symptom burden compared to a wait-list control?
Does AIR improve sleep disturbance, vasomotor symptom interference, fatigue, mood, anxiety, and quality of life in perimenopausal individuals?
Are symptom changes associated with improvements in autonomic regulation and sleep parameters, as reflected by exploratory wearable measures including heart rate variability?
Eligibility criteria
Qualifiers
Experiencing perimenopausal symptoms
Meets STRAW+10 criteria based on self-assessment (-2 to +1c)
Able to read and understand English
Access to internet
Disqualifiers
Pregnancy
Presence of a severe psychiatric condition requiring immediate clinical intervention
Uncontrolled thyroid disease or prolactinoma
Active cancer treatment
Trial design
Treatments tested in this trial
- Amygdala and Insula Retraining (AIR)
Treatment groups
160 Participants
are divided into 2 treatment groupsSponsors and collaborators
Source ClinicalTrials.gov