An Exploratory Clinical Study on the Protective Effect of Cycling on the Ankle Joint in Gout
Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-60
SponsorZhu Xiaoxia
About this trial
This study divided the enrolled gout patients into a jogging group and a cycling group to investigate 1）the effectiveness of cycling intervention in reducing the recurrence risk of gouty ankle arthritis compared with jogging. 2) To clarify the influence of different exercise patterns on the ultrasonic manifestations of gouty ankle arthritis; 3) Clarify the impact of different exercise methods on the blood uric acid levels of gout patients;
Eligibility criteria
Qualifiers
meets the diagnostic criteria for gout of the American College of Rheumatology (ACR) and the European League Against Rheumatism (EULAR) in 2015
There have been two histories of gout attacks on either side of the ankle joint in the past six months
Ultrasound examination within the past 6 months indicated that either ankle joint had characteristic ultrasound manifestations (double-track sign, and/or hyperechoic aggregates, and/or tophi, and/or bone destruction)
Those who have had an interval of at least 4 weeks since the most recent acute gout attack
Disqualifiers
Those who have received intra-articular injections of corticosteroids during an attack within the past three months; Those who have taken colchicine, NSAIDs, glucocorticoids in the past two weeks, or those who need to maintain anti-inflammatory drug treatment for a long time during the follow-up period
Joint trauma or other types of arthritis
There is a history of joint prosthesis or joint surgery
Those who have had acute gout attacks within 4 weeks
Trial design
Treatments tested in this trial
- Urate-lowering therapy (ULT)
- Jogging
- Cycling
Treatment groups
90 Participants
are divided into 2 treatment groupsLocations
Sponsors and collaborators
Zhu Xiaoxia
Lead sponsor
Huashan Hospital
Sponsor institution
Source ClinicalTrials.gov