About this trial
The goal of this observational study is to improve the early detection of lung cancer in adults who have smoked less than 100 tobacco cigarettes ("never-smokers") in the United Kingdom. The main questions it aims to answer are:
* To describe characteristics such as demographics, co-morbidities and environmental exposures * To describe participant pathways including presentation mode and symptoms to understand if earlier diagnosis would be possible * To describe participant outcomes such as cancer stage, treatment and mortality * To quantitatively or qualitatively measure modifiable and non-modifiable factors that may be associated with LCINS including environmental measures, blood tests and genomic data.
Participants will currently have no change to their usual care.
Eligibility criteria
Qualifiers
All adult participants from age of 18 who are diagnosed or treated with primary lung cancer through radiology or histology at any participating study site
Disqualifiers
More than 100 cigarettes or 75g tobacco in their lifetime
Those who have received a prescription for nicotine replacement therapy
For prospective participants, those who cannot consent will be excluded
Trial design
Treatments tested in this trial
- Not listed
Trial groups
Sponsors and collaborators
University College London Hospitals
Lead sponsor
University College, London
Sponsor institution