About this trial
To demonstrate that intervention targeting the supplementary motor area (SMA) using precise navigation positioning can effectively improve motor symptoms in patients with Parkinson's disease.
Eligibility criteria
Qualifiers
Age ≥40 years old
Meet Movement Disorder Society standards;
Have no history of drug adjustment within 4 weeks before and during treatment;
The MDS-UPDRS Ⅲ score ≥8, and the Hoehn-Yahr rating is 1-4
Disqualifiers
Head MRI/CT ruled out focal brain injury or severe leukoencephalopathy (Fazekas grade 3);
Various secondary parkinsonism syndromes (vascular parkinsonism, Parkinsonism combined with parkinsonism, drug parkinsonism, etc.);
Severe craniocerebral trauma, received craniocerebral surgery or deep brain stimulation treatment;
There are ferromagnetic implants in the body, such as cochlear implants, cardiac pacemakers, etc.
Trial design
Treatments tested in this trial
- transcranial magnetic stimulation