Analgesia-First Sedation in Trauma Patients
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorMemorialCare Health System
About this trial
The study's aim is to ascertain the best approach for providing sedation and pain management for patients who have sustained trauma and are requiring respiratory support from a mechanical ventilator. The common approach to patients who need mechanical ventilation is to provide continuous drips of sedatives and pain medicine and awaken the patient once a day to check the brain functions. Another approach is to provide pain medicine and reserve sedatives for only a short duration when needed. The difference between approaches has not been studied in Trauma patients.
Eligibility criteria
Qualifiers
≥ 18 years of age
Mechanically ventilated with an expected duration of MV ≥ 48h
Initiated continuous sedative/analgesic infusions by the ICU team
Patient is a candidate for MV weaning
Disqualifiers
Admission after resuscitation from cardiac arrest
Significant neurological deficit due to a chronic disorder
History of alcohol dependence and/or other illicit drug abuse
Prior administration of continuous sedative/analgesic from a transferring institution
Trial design
Treatments tested in this trial
- Analgesia First Sedation Strategy for Mechanically Ventilated (MV) Trauma Subjects
- Protocol Directed Sedation and Daily Sedation Interruption
Treatment groups
170 Participants
are divided into 2 treatment groupsSponsors and collaborators
Source ClinicalTrials.gov