Analgesia Nociception Index to Explore Autonomic Nervous System in Patients With Continuous Renal Replacement Therapy
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorHospices Civils de Lyon
About this trial
The Analgesia Nociception Index (ANI) reflects the balance between sympathetic and parasympathetic tone. It is based on a specific interpretation of the R-R interval variation. During fluid removal by net ultrafiltration in patients with fluid overload and continuous renal replacement therapy, some data suggest that haemodynamic variation could be induced by the autonomic nervous system. The study aims to investigate ANI variations in this context and their association with the haemodynamic variations observed.
Eligibility criteria
Qualifiers
Continuous renal replacement therapy in intensive care unit
Fluid overload > 5% or peripheral oedema
Noradrenaline equivalent <0.5μg/kg/min
No peripheral hypoperfusion
Disqualifiers
Ongoing administration of inotropes
Ongoing administration of beta blockers
Current administration of alpha-2 agonists
History of dysautonomia
Trial design
Treatments tested in this trial
- Not listed
Trial groups
30 Participants
are grouped into 1 trial groupSponsors and collaborators
Source ClinicalTrials.gov