The purpose of this study is to see whether dried blood spot (DBS) samples can measure inflammatory biomarkers as accurately as venous blood samples.
Investigators will be measuring inflammatory biomarkers changes obtained in DBS compared with paired venous blood samples following a controlled physiological stressor (i.e. after a vaccine or other planned event that can cause a temporary rise in inflammation).
These findings will help understand whether DBS can be a reliable alternative to traditional blood draws in future research and healthcare.
Men or women aged ≥18 years, who are planning to receive a seasonal vaccine OR have a scheduled acute stressor*.
Any infectious symptoms (fever, cough, rhinorrhea, sore throat, diarrhea, loss of smell or taste) within the previous 7 days
Any self-reported active/recent use of cocaine, injection drugs, or amphetamines
Acute worsening of a known chronic health condition within the previous 30 days (e.g., of IBD, COPD, asthma, rheumatologic disease)
Known severe allergy or intolerance to the planned vaccine
McGill University Health Centre/Research Institute of the McGill University Health Centre
Lead sponsor
Sensifai Health
Collaborator