Analysis of the Composition of the Intestinal Microbiota in Patients Post-intestinal Anastomosis

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorInstituto de Investigación Sanitaria de la Fundación Jiménez Díaz

About this trial

Recent research suggests a significant link between gut microbiota and anastomotic leakage (AL) in colorectal surgery. Patients who develop AL have a higher abundance of bacteria from the Lachnospiraceae family and lower microbial diversity.

Considering the bibliographic data, our main interest is to analyze the microbial population of patients in our social environment and then look for differences in the microbiome between those who have suffered an anastomotic dehiscence (around 8-9% according to the results of our hospital's Surgery Department) and those who have not.

Eligibility criteria

Qualifiers

Patients who have undergone colorectal intestinal anastomosis.

Signing of the informed consent form.

Age ≥18 years with good functional status.

Availability for postoperative follow-up.

Disqualifiers

Emergency surgery.

Intra-abdominal sepsis or previous dehiscence.

Severe immunosuppression.

Use of antibiotics in the 3 months prior to preoperative preparation.

Trial design

Treatments tested in this trial

  • Not applicable- observational study

Treatment groups

30 Participants
are divided into 1 treatment group