Analysis of the Loss of Muscle Force, Power and Motor Control to Predict the Risk of Falls in Patients With Knee OA

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age65-80
SponsorIstituto Ortopedico Rizzoli

About this trial

The twofold goal of this study is to understand the link between muscle power, muscle strength, and muscle control degradation with the risk of falling, and to develop a framework for the comprehensive and quantitative assessment of muscle power (and strength) in an elderly population of patients with knee osteoarthritis, who are at higher risk of falling. The main question it aims to answer is:

● Are muscle power and motor control degradation better predictors of falls than muscle strength in the aging population?

Participants will undergo:

* Muscle force assessment on a dynamometer * Muscle power assessment on a dynamometer and on isntrumented stairs * Home-based mobility monitoring * Full lower limb MRI acquisition * Gait assessment

Eligibility criteria

Qualifiers

Age between 65 and 80 years

Kellgren score II e III

No history of falls in the last 12 months

Disqualifiers

Any musculoskeletal, neurological, rheumatic or tumoral diseases

Dementia

Diabetes

Inguinal or abdominal hernia

Trial design

Treatments tested in this trial

  • Muscle power assessment
  • Muscle force assessment
  • Home-based mobility monitoring
  • Magnetic Resonance Imaging
  • Gait assessment

Treatment groups

50 Participants
are divided into 1 treatment group

Sponsors and collaborators