Analysis of Urinary Methylation Patterns Via Liquid Biopsy as an Early Diagnosis Tool
ConditionBladder Cancer
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorRegina Elena Cancer Institute
About this trial
Multicenter, observational, prospective, biological pilot study on liquid biopsy, aimed at investigating methylation profiles in relation to the early diagnosis of bladder cancer, to validate the potential of commercially available tests (e.g. BladderCARE, Bladder EpiCheck), to apply and validate tests based on targeted multi-marker or genome wide analyzes via NGS and to identify methylation profiles as a tool to infer clinical outcome.
Eligibility criteria
Qualifiers
age ≥ 18 years
proven diagnosis of bladder cancer (infiltrating muscle or non-infiltrating muscle)
performance status (PS) 0-1
ability to follow the procedures established by the study
Disqualifiers
presence of metastatic bladder cancer
lack of autonomy in following the procedures established by the study
previous or current clinical history associated with bladder cancer
diagnostic suspicion associated with tumor pathologies
Trial design
Treatments tested in this trial
- Not listed
Trial groups
100 Participants
are grouped into 2 trial groupsSponsors and collaborators
Regina Elena Cancer Institute
Lead sponsor
Azienda Ospedaliera Santa Maria Degli Angeli
Collaborator
Istituto per lo Studio, la Prevenzione e la Rete Oncologica
Collaborator
Source ClinicalTrials.gov