Anatomical Axis on X-Ray and Its Relationship With Pain and Kinesiophobia in Knee Osteoarthritis
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorSelim Sezikli
About this trial
Knee osteoarthritis is a common joint disease that causes pain, stiffness, and limitations in daily activities, especially in older adults. Changes in the alignment of the lower limb, called the anatomical axis, can increase the mechanical load on the knee joint and may affect pain and mobility. This study aims to investigate the relationship between the anatomical axis measured on knee X-rays and patients' pain levels, functional status, quality of life, and fear of movement (kinesiophobia).
This is a single-center, observational, cross-sectional study. Adult patients diagnosed with knee osteoarthritis who have a standard knee X-ray taken within the last 6 months and who volunteer to participate will be included. Pain will be measured with the Visual Analog Scale (VAS), functional status with the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC), quality of life with the 36-Item Short Form Health Survey (SF-36), and kinesiophobia with the Tampa Scale for Kinesiophobia (TSK). The femoro-tibial angle and joint space width will be measured on X-rays by two independent observers.
By examining the relationship between radiographic alignment and clinical findings, this study may provide new insights into the comprehensive evaluation of knee osteoarthritis and help guide treatment planning for patients.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
Diagnosis of knee osteoarthritis (clinical and radiographic)
Having an anteroposterior knee X-ray taken within the last 6 months
Voluntary agreement to participate in the study
Cognitive ability sufficient to understand test instructions
Disqualifiers
History of knee surgery
Illiteracy (inability to read/write)
Refusal to participate
Presence of orthopedic conditions that prevent walking (e.g., amputation, joint prosthesis)
Trial population
Adult patients diagnosed with knee osteoarthritis who are admitted to the Physical Medicine and Rehabilitation outpatient clinics of Istanbul Physical Medicine and Rehabilitation Training and Research Hospital. Participants must have a knee X-ray taken within the last 6 months and meet the study's eligibility criteria.
Trial design
Design model
Cohort
Time perspective
Cross-sectional
Treatments tested in this trial
Not listed
Trial groups
100 Participants
are grouped into 1 trial groupGroup A: Knee Osteoarthritis Patients
Trial outcomes
Primary outcomes
1
Pain Severity Assessed by Visual Analog Scale (VAS)
Pain intensity during daily activities will be assessed using a 10-cm Visual Analog Scale (VAS), where 0 indicates "no pain" and 10 indicates "worst imaginable pain.
Time frame
Day 1 (single assessment at baseline)2
Kinesiophobia Assessed by Tampa Scale for Kinesiophobia (TSK)
Fear of movement will be measured with the Tampa Scale for Kinesiophobia (TSK), a validated questionnaire widely used in musculoskeletal conditions.
Time frame
Day 1 (single assessment at baseline)Secondary outcomes
1
Functional Status Assessed by Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC)
Functional status, stiffness, and pain will be assessed using the WOMAC index, a validated tool for patients with knee osteoarthritis.
Time frame
Day 1 (single assessment at baseline)2
Quality of Life Assessed by Short Form-36 (SF-36)
General health-related quality of life will be evaluated using the SF-36, a standardized questionnaire covering physical, emotional, and social domains.
Time frame
Day 1 (single assessment at baseline)3
Radiographic Alignment Assessed by Femoro-Tibial Angle (FTA)
The anatomical axis of the lower limb will be measured on standard anteroposterior knee radiographs by two independent observers.
Time frame
Day 1 (single assessment at baseline)4
Joint Space Width (JSW) on Knee X-Ray
Medial and lateral joint space width will be measured on radiographs to evaluate structural severity of knee osteoarthritis.
Time frame
Day 1 (single assessment at baseline)Sponsors and contacts
Click on the lead sponsor to view all of their trials.
Selim Sezikli
Lead sponsor
Istanbul Physical Medicine Rehabilitation Training and Research Hospital
Sponsor institution
Source ClinicalTrials.gov