Antagonism of Neostigmine in Continuous Infusion of Mivacurium
ConditionNeuromuscular Blocking Agents
Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-65
SponsorBeijing Tongren Hospital
About this trial
In this study, the antagonism of neostigmine, a cholinesterase inhibitor, on continuous infusion of mivacurium during foot and ankle surgery under general anesthesia was investigated, and the appropriate time point of antagonism was explored.
Eligibility criteria
Qualifiers
18 - 65 years old;
American Society of Anesthesiologists (ASA) physical stastus classification system: I-II;
Body mass index (BMI) 18.5 - 30 kg/m2
Patients with normal cholinesterase levels before the operation
Disqualifiers
Refusal to participate in the study;
ASA classification of grade III or above;
Severe organ dysfunction, difficult airway or neurological muscle disorders;
Taking drugs that affect neuromuscular monitoring or neuromuscular conduction function;
Trial design
Treatments tested in this trial
- Neostigmine
Treatment groups
120 Participants
are divided into 3 treatment groupsSponsors and collaborators
Source ClinicalTrials.gov