About this trial
This prospective observational study aims to evaluate the effect of antegrade pump blood reinfusion using the crystalloid "chase" technique on postoperative transfusion requirements in adult patients undergoing cardiac surgery with cardiopulmonary bypass. At the end of cardiopulmonary bypass, blood remaining within the cardiopulmonary bypass circuit is reinfused antegradely through the arterial line using a crystalloid chase, without collection or storage. Blood remaining within the bypass circuit after surgery represents a valuable source of autologous blood, and its reinfusion may contribute to perioperative blood conservation strategies. Patients receiving antegrade pump blood reinfusion via the chase technique will be compared with those managed without reinfusion, without any intervention by the investigators. The primary outcome is postoperative blood transfusion requirement.
Eligibility criteria
Qualifiers
Age 18 to 80 years
Patients undergoing elective, isolated coronary artery bypass grafting surgery using cardiopulmonary bypass (on-pump).
Disqualifiers
Emergency or Redo cardiac surgery
Concomitant cardiac procedures (e.g., valve repair/replacement or aortic surgery).
Planned or intraoperative conversion to off-pump coronary artery bypass grafting
Preoperative hematocrit <30% or known inherited/acquired bleeding disorders.
Trial design
Treatments tested in this trial
- Antegrade Pump Blood Reinfusion
- No Anterograde Pump Blood Reinfusion