Antibacterial Efficacy of Bioceramic and Calcium Hydroxide Intracanal Medicaments
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-65
SponsorMedipol University
About this trial
This study evaluates the antibacterial effectiveness of two different intracanal medicaments, Bio-C Temp and UltraCal XS , in mandibular molar teeth with chronic apical periodontitis. Intracanal bacterial load is assessed before and after root canal preparation, after intracanal medicament removal, and after final irrigation using droplet digital PCR.
Eligibility criteria
Qualifiers
Patients aged between 18 and 65 years
Being systemically healthy (ASA I or ASA II)
Mandibular molar teeth with a radiographically detectable radiolucent lesion in the periapical region
Willingness of the volunteer or their legal representative to participate in the study by signing the Informed Consent Form
Disqualifiers
Patients who have received antibiotics or corticosteroids within the last 3 months
Patients with systemic diseases
Teeth that cannot be properly isolated with a rubber dam
Teeth with periodontal pockets >4 mm and teeth with crown/root fractures
Trial design
Treatments tested in this trial
- Root canal treatment with Bio-C Temp, a calcium silicate-based bioceramic intracanal medicament
- Root canal treatment with UltraCal XS, a calcium hydroxide-based intracanal medicament
Treatment groups
24 Participants
are divided into 2 treatment groupsSponsors and collaborators
Source ClinicalTrials.gov