Antibiotic Irrigation and Suction Ureteral Access Sheath in RIRS
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorHitit University
About this trial
Retrograde intrarenal surgery (RIRS) is a widely used treatment for kidney stones; however, postoperative infectious complications remain a significant concern. This prospective randomized factorial trial aims to evaluate whether gentamicin-containing irrigation fluid and the use of a suction ureteral access sheath can reduce postoperative fever, systemic inflammatory response syndrome (SIRS), and sepsis after RIRS. The study will also investigate the independent and combined effects of these two interventions on infectious outcomes.
Eligibility criteria
Qualifiers
Patients scheduled for retrograde intrarenal surgery (RIRS) due to kidney stones
Male and female patients aged 18 years or older
Patients who voluntarily sign the informed consent form
Patients with sterile urine culture or whose preoperative infection has been treated and urine culture has become sterile
Disqualifiers
Patients with active urinary tract infection before surgery
Patients with chronic kidney disease
Pregnant patients
Patients with allergy to aminoglycoside-group drugs used in the study protocol, specifically gentamicin
Trial design
Treatments tested in this trial
- Standard Retrograde Intrarenal Surgery
- Gentamicin Irrigation
- Suction-Enabled Ureteral Access Sheath
Treatment groups
180 Participants
are divided into 4 treatment groupsSponsors and collaborators
Source ClinicalTrials.gov