To explore surgical strategies that reduce perioperative neurologic complications in cardiovascular surgery, with the aim of improving perioperative outcomes and quality of life while reducing the socioeconomic burden. Specifically:
This multicenter, randomized controlled clinical trial will evaluate the benefits of a novel aortic no-touch technique in reducing perioperative silent brain infarction(SBI) among patients undergoing surgical treatment for coronary artery disease. The findings are expected to provide a safe and effective myocardial revascularization strategy for individuals at high risk of cerebral ischemia.
Adult patients (>18 years old) with multivessel coronary artery disease who are scheduled to undergo isolated off-pump coronary artery bypass grafting and who provide informed consent to participate in this study.
Indications for cardiopulmonary bypass surgery (or no contraindications to on-pump surgery);
Great saphenous vein is unsuitable for use as a graft conduit;
Subclavian artery stenosis or occlusion, or any contraindication to the use of the internal mammary artery as a graft conduit;
History of previous cardiac surgery;