Aortic Stiffness in Patients With Genetic Aortopathies
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
AgeNot listed
SponsorIRCCS Policlinico S. Donato
About this trial
The goal of this observational study is to study arterial stiffness in patients with thoracic ascending aortic aneurysms (TAA), either syndromic or non-syndromic. The main questions it aims to answer are:
* Stratification of aortic risk based on arterial stiffness; Compare measurements with morphological and haemodynamic features of the ascending thoracic aorta.
Participants will be asked to undergo non-invasive evaluation of blood pressure and arterial stiffness.
Eligibility criteria
Qualifiers
Subjects with AAT, either syndromic or non syndromic;
Signed informed consent
Disqualifiers
Patients with early menopause and/or osteoporosis, rheumatic heart disease and active malignant tumours;
Patients with acute and chronic inflammatory conditions such as: chronic liver disease, chronic renal insufficiency and diseases affecting the thyroid system;
Seropositivity to HIV, HCV, HBsAg and SARS-CoV-2;
Pregnancy
Trial design
Treatments tested in this trial
- Pulsotonometry
Treatment groups
250 Participants
are divided into 2 treatment groupsSponsors and collaborators
IRCCS Policlinico S. Donato
Lead sponsor
Istituto Auxologico Italiano
Collaborator
Source ClinicalTrials.gov