Appalachian Partnership to Reduce Disparities (Aim 2)

ConditionsHIV/AIDSSTIHCV
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorWake Forest University Health Sciences

About this trial

By combining two strategies (i.e., peer navigation and mHealth) into a complete, culturally compatible, bilingual intervention to increase the use of needed HIV, STI, and HCV prevention and care services among racially/ethnically diverse GBMSM and transgender women in rural Appalachia.

Study Investigators anticipate that participants in the intervention group, relative to counterparts in the delayed-intervention group, will demonstrate increased HIV, STI, and HCV testing.

Eligibility criteria

This trial accepts healthy volunteers

Qualifiers

reside in one of the rural Appalachian catchment countiesreside in one of the rural Appalachian catchment counties

be ≥18 years of age

report being assigned male sex at birth and having had sex with at least 1 man in past 12 months

provide informed consent

Disqualifiers

None

Trial design

Design model

Parallel

Treatments tested in this trial

  • Peer Navigation

    Behavioral

    First, as health advisors, community health leaders will raise awareness of HIV, STIs, and HCV and local prevention and care services and help social network members access services. Thus, the community health leader will describe to the process for HCV testing, and how providers are required to maintain confidentiality. As opinion leaders, community health leaders will reframe health-compromising and bolster health-promoting norms and expectations about testing and use of other prevention and care services. Each community health leader will also conduct formal in-person group activities with their social network members. Our partnership decided that each community health leader will also hold at least 4 formal group sessions during the 12 months of intervention

  • mHealth

    Behavioral

    In addition to in-person individual and group activities, community health leaders will use mHealth platforms preferred by each social network member (i.e., Facebook , Instagram, testing, and/or GPS-based mobile apps) to communicate with them during the intervention. They will use social media to plan activities and to support use of needed prevention and care services. For example, when planning a group activity (described above), the community health leader will use social media to remind social network members about the activity and help them problem solve barriers to attending. A community health leader and social network member may also communicate "in-real-time" via social media about the process of participating in a syringe services program or accessing PrEP.

Treatment groups

141 Participants
are divided into 2 treatment groups
Group A: intervention groupActive comparator 2 interventions
Group B: delayed-interventionActive comparator 2 interventions

Trial outcomes

Primary outcomes

1

Number of participants who have Human Immunodeficiency Virus (HIV) testing

Time frame
baseline
2

Number of participants who have Sexually Transmitted Infection (STI) testing

Time frame
baseline
3

Number of participants who have Hepatitis C Virus (HCV) testing

Time frame
baseline
4

Number of participants who have HIV testing

Time frame
immediate post-intervention (12 months post-baseline)

Secondary outcomes

1

Number of participants who use prevention--Pre-exposure prophylaxis (PrEP)

Time frame
baseline, immediate post-intervention (12 months post-baseline), and 12-month follow-up (24 months post-baseline).
2

Number of participants who use prevention--syringe services

Time frame
baseline, immediate post-intervention (12 months post-baseline), and 12-month follow-up (24 months post-baseline).
3

Number of participants who use HIV care services

Measured through self-report and medical chart abstraction

Time frame
baseline, immediate post-intervention (12 months post-baseline), and 12-month follow-up (24 months post-baseline).
4

Number of participants who use STI treatment services

Measured through self-report and medical chart abstraction

Time frame
baseline, immediate post-intervention (12 months post-baseline), and 12-month follow-up (24 months post-baseline).

Other outcomes

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

Wake Forest University Health Sciences

Lead sponsor

National Institute of Nursing Research (NINR)

Collaborator