Application of HFNC for the Prevention of Hypoxemia During Perioperative Anesthetic-induced Intubation in Children: A Randomized Controlled Clinical Trial

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age2-10
SponsorHenan Provincial People's Hospital

About this trial

Compared with adults, children have higher metabolic needs, and the airway is more likely to collapse. Before tracheal intubation after anesthesia induction, the patient 's spontaneous breathing completely disappears. At this critical stage, the residual oxygen of the lung is consumed, resulting in hypoxemia and atelectasis. Therefore, it is necessary to explore the best oxygenation strategy during intubation. In addition, ultrasound has become a common equipment in the operating room. It has the advantages of portability, repeatability, and no radiation, and can provide strong support for the diagnosis of gastric distension.

Eligibility criteria

Qualifiers

Age 2-10 years old;

American Society of Anesthesiologists (ASA) Level I or II;

Children with healthy lungs and hearts;

Clear headed and able to cooperate with anesthesiologists for treatment.

Disqualifiers

Contraindications for HFNC: (1) Complete obstruction of the upper respiratory tract; (2) Skull base fracture or nasal bone fracture; (3) Patients who refuse to use HFNC;

The American Society of Anesthesiologists (ASA) rating is greater than Level II;

Children with upper respiratory tract infections within 2 weeks;

Pulmonary dysfunction, congenital heart disease in children;

Trial design

Treatments tested in this trial

  • high-flow nasal cannula

Treatment groups

48 Participants
are divided into 2 treatment groups