Application of Remimazolam, Dexmedetomidine, and Esketamine in Pediatric Preoperative Sedation

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age2-5
SponsorMaternal and Child Health Hospital of Hubei Province

About this trial

By comparing the application effects of three drugs in pediatric preoperative sedation, this study explores the optimal medication regimen, aiming to provide safer, more effective, and more personalized medication options for pediatric preoperative sedation. Additionally, this research will also focus on the impact of these three drugs on postoperative agitation in children, offering valuable references for the overall management of pediatric surgical anesthesia.

Eligibility criteria

Qualifiers

Children aged 2 to 5 years old

the American Society of Anesthesiologists (ASA) physical status of Class I

scheduled for adenotonsillectomy under general anesthesia, will be included.

Disqualifiers

Abnormal lung function and respiratory system function

airway obstruction or deformity, history of mental illness

electrocardiogram indicating bradycardia

history of cardiac disease

Trial design

Treatments tested in this trial

  • remimazolam group
  • dexmedetomidine group
  • esketamine group

Treatment groups

150 Participants
are divided into 3 treatment groups