Application of THRIVE in Burn Children With Suspected Difficult Airway

Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
AgeUp to 18
SponsorShuxiu Wang

About this trial

In order to improve intubation conditions in burn children, our aim is to investigate the efficacy of transnasal humidified rapid-insufflation ventilatory exchange technique(THRIVE) in children aged between 0 and 18 years who with head, face, and neck injuries by fire, scalding, chemical, electric,explosions, and others. We hypothesise that THRIVE increases first attempt success without hypoxemia in intubation of children and compared with routine practice.

Does the THRIVE can prolong apnoea time and delay the onset of desaturation to increase the success rate of the first tracheal intubation without desaturation?

Researchers will compare THRIVE group with Routine care group to see successful intubation on the first attempt without desaturation.

Participants will received intravenous anesthesia induction, followed by 2-3 minutes preoxygenation, before intubation, the mask was removed from the children's face and a THRIVE nasal plug was placed. During intubation, the Routine care group had no oxygen supply,and the THRIVE group will be maintained throughout the apnoeic period with selected flow rates during intubation attempts.

Eligibility criteria

Qualifiers

< 18 years

ASA Grade I ~ III

Children with head, face and neck scald or burn or flame or electrical c hemical or other

Disqualifiers

Refusal or failure to sign an informed consent

Proposed to transnasal intubation

Fracture of the nasal bone, nasal bleeding, nasal deformity or obstruction

Tracheotomy status or severe head, face and neck burn or burn scar (difficult airway)

Trial design

Treatments tested in this trial

  • Transnasal humidified rapid-insufflation ventilatory exchange (THRIVE)

Treatment groups

120 Participants
are divided into 2 treatment groups

Locations

This trial has no locations

Sponsors and collaborators

Shuxiu Wang

Lead sponsor

The First Affiliated Hospital of Air Force Medicial University

Sponsor institution