Application of Ultra-high Frequency Ultrasonography (UHFUS) to the Study of Gingival Tissues

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18-70
SponsorUniversity of Pisa

About this trial

Gingival inflammation triggered by the accumulation of bacterial is the primary risk factor for the development of periodontitis. Clinically, localized signs of inflammation limited to the gingiva, presence of significant bacterial plaque load, and stable attachment levels on the periodontium can be observed in course of gingivitis. The aim of the present study is to compare clinical aspects of gingival tissue in healthy patients versus patients with gingivitis to assess the ultrastructural variations present in course of inflammation.

Patients with gingivitis and healthy controls will be enrolled. All patients will undergo ultra-high frequency ultrasonographic scans (70 MHz) of gingival tissue on three areas per dental arch (anterior, middle right, middle left). Gingival thickness, echogenicity, and vascularization assessed through resisitive index will be evaluated.

Eligibility criteria

Qualifiers

males or females of age > 18 years

presence of at least 20 teeth

full-mouth plaque score (FMPS) >50%

FMBS >30%

Disqualifiers

pregnancy or breastfeeding

pharmacological treatment with antinflammatory drugs, statins, or either local or systemic antibiotics (within the previous 30 days)

smoking habit

dental or periodontal condition requiring immediate treatment

Trial design

Treatments tested in this trial

  • Performance of ultrasonographic scan

Treatment groups

40 Participants
are divided into 2 treatment groups

Sponsors and collaborators