Arterial Spin Labeling MRI for Assessing Blood Perfusion in the Human Eye Repeatability Study and Clinical Application

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorCliniques universitaires Saint-Luc- Université Catholique de Louvain

About this trial

The MRI perfusion imaging using arterial spin labeling (ASL)'s non-invasive technique (i.e. without injection of contrast medium) allows, thanks to recent technological improvement of the spatial resolution, measuring several perfusion parameter of the retinal tissue such as the regional Blood Flow (rBF) or the cerebral blood flow (cBF) expressed in ml/100g/min. Reliable application of ASL thus requires the precision and specificity of the MRI protocol to be tested.

Eligibility criteria

Qualifiers

Carrier of target pathologies: TAO optic neuropathy, inflammatory optic neuropathy, ischemic optic neuropathy.

no cardiovascular risk factors or other ophthalmological pathology

adhere to the study protocol after reading the patient information document

signe the informed consent form to participate in the study

Disqualifiers

Usual contraindications to MRI (Pacemaker, Metallic foreign body, Cochlear implant,…)

Severe claustrophobia

Trial design

Treatments tested in this trial

  • MRI perfusion imaging using ASL's non-invasive technique

Treatment groups

70 Participants
are divided into 3 treatment groups