Arterial Stiffening as a Predictor for Diastolic Cardiac Dysfunction and HFpEF

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorUniversity Medical Center Goettingen

About this trial

Patients at risk for developing heart failure with preserved ejection fraction (HFpEF) will undergo a structured clinical assessment, transthoracic echocardiography and pulse-wave analysis to investigate the association of arterial stiffening and the development of cardiac diastolic dysfuntion and HFpEF.

Eligibility criteria

Qualifiers

Age > 60 years

Arterial hypertension (RR systolic ≥ 140 mmHg or diastolic ≥ 90 mmHg or ≥ 2 antihypertensive drugs)

Diabetes mellitus Type I or II

Atrial fibrillation

Disqualifiers

Left ventricular ejection fraction < 50 %

Significant valve disease (Grade III or higher)

History of interventional or surgical valve repair

Regional wall motion abnormalities

Trial design

Treatments tested in this trial

  • Not listed

Trial groups

No trial groups listed