Artificial Intelligence (AI)-Enhanced Pretreatment Peer-review Process to Improve Patient Safety in Radiation Oncology

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorUNC Lineberger Comprehensive Cancer Center

About this trial

This prospective study will test artificial intelligence (AI) and machine learning (ML) decision support tools. This tool is designed to help doctors, physicists and other staff during pre-treatment peer review, a step where treatment plans are checked before a patient begins care.

The system highlights summaries showing how different providers may vary in their treatment planning (provider-variability summaries) and points out the best signals or warning signs to look for (optimal cues). By drawing attention to these patterns and cues, the tool aims to help reviewers spot possible treatment-planning mistakes earlier, reduce the chance of errors, and improve overall patient safety.

Eligibility criteria

This trial accepts healthy volunteers

Qualifiers

≥18 years

Peer-review attendees at participating clinics

≥18 years

All patients with prostate cancer radiation therapy cases treated at participating sites (no intervention delivered to patients)

Disqualifiers

None

Trial design

Design model

Parallel

Treatments tested in this trial

  • The Artificial Intelligence (AI)/ Machine Learning (ML) contribution to treatment planning

    Device

    All treatment planning and clinical monitoring are conducted in accordance with institutional standards and established departmental policies. Peer review activities proceed as they would in routine clinical practice, with the addition of optional Artificial Intelligence (AI) generated analytics available for clinician review. AI / Machine Learning (ML) system is embedded in scheduled departmental peer review meetings and presents analytic summaries and visualizations through a dashboard that is integrated into the existing clinical workflow. The system functions solely as a decision support aid and does not perform or initiate any autonomous treatment planning actions, dose delivery changes, or clinical interventions. During simulation (SIM) review, physician generated target and organ at risk contours are reviewed first, consistent with standard practice. Only after this initial review may the treating physician optionally access the AI generated contours for comparative purposes.

Treatment groups

207 Participants
are divided into 2 treatment groups
Group A: ProvidersOther 1 intervention
Group B: PatientsNo intervention 0 interventions

Trial outcomes

Primary outcomes

1

Percentage of patients with changes nodal volume contours

Percentage of patients with documented changes regarding nodal volume contours after Artificial Intelligence (AI) enhanced peer review.

Time frame
Baseline

Secondary outcomes

Other outcomes

Sponsors and contacts

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UNC Lineberger Comprehensive Cancer Center

Lead sponsor

Agency for Healthcare Research and Quality (AHRQ)

Collaborator