Asian Multicenter Prospective Study in HER2 Positive Early Breast Cancer for Detecting MRD by ctDNA;HARMONY Study

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age20+
SponsorNational Cancer Center, Japan

About this trial

This study will assess minimal residual disease (MRD) in HER2-positive early breast cancer patients in Asian countries. The purpose is to evaluate the relation between the detection rate of MRD and recurrence.

Eligibility criteria

Qualifiers

Age of 20 years or older at the date of registration.

Histological diagnosis of HER2-positive invasive breast carcinoma.

Patients scheduled for neoadjuvant chemotherapy followed by surgery.

Clinical Stage IIA-IIIC.

Disqualifiers

Any other malignancy within 5 years prior to registration, except for adequately treated basal cell or squamous cell skin cancer, or carcinoma in situ of the esophagus, stomach, colon, or cervix.

Bilateral synchronous breast cancer.

History of breast cancer.

Pregnancy at registration.

Trial design

Treatments tested in this trial

  • Not listed

Trial groups

No trial groups listed

Locations

1

Map coordinates are unavailable for these locations. Locations are shown below instead.

National Cancer Center Hospital, JapanRecruiting104-0045, Chuo-ku, TokyoJapanJapan

Sponsors and collaborators