This retrospective cohort study evaluates the association between H. pylori persistence and insulin resistance severity (HOMA-IR) in 100 patients with metabolic syndrome at Novosibirsk's Center for New Medical Technologies (CNMT). Patients are divided into infected (n=50) and non-infected (n=50) groups, assessing metabolic parameters, gastro panel, and CRP. Primary endpoint: HOMA-IR differences; secondary: correlations with gastric inflammation and metabolic markers.
Verified MS per NCEP-ATP III criteria.
Ability to undergo all procedures (fasting blood draw, breath test, stool antigen, endoscopy/biopsy, anthropometry).
Current metabolic-influencing therapy.
Acute/chronic infection or autoimmune flare.
Interventional study participation in last 3 months.
Planned surgery/long hospitalization.
Center of New Medical Technologies
Lead sponsor
Novosibirsk State University
Collaborator