The investigators propose a randomized controlled trial to evaluate the clinical effectiveness of low-dose computed tomography (LDCT) for lung cancer screening in high-risk Chinese ever-smokers aged 50-79 years in Hong Kong and to assess the cost-effectiveness of implementing LDCT for lung cancer screening in the local setting.
Adults aged between 50 and 79 years
Current smokers or ex-smokers quitted for less than 10 years, with a history of cigarette smoking equivalent to at least 20 pack-years
Non-Chinese population
Individuals who are not mentally competent to provide informed consent (e.g., those with a history of dementia)
Individuals with a known prior diagnosis of lung cancer or detection of lung nodules
Individuals with a history of other cancers within the last five years or currently under treatment
The University of Hong Kong
Lead sponsor
The Hong Kong Jockey Club Charities Trust
Collaborator