Assessing the Effects of Photobiomodulation on Clinical Recovery From Concussion in Adolescents

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age13-18
SponsorThe University of Texas Health Science Center, Houston

About this trial

The purpose of this study is to compare effects of Photobiomodulation therapy (PBMt) to standard of care in adolescent athletes at risk for delayed recovery from subacute sports concussion, to substantiate the impact of subacute PBMt over time on functional and structural connectivity of the brain using advanced MRI sequences and to correlate the psychological and behavioral outcomes to neuroimaging findings

Eligibility criteria

Qualifiers

current participants in a school- or club-sponsored sport (contact or non-contact)

access to wireless internet service at home

diagnosis of sports-related concussion (SRC) (according to consensus diagnostic criteria) by a licensed healthcare provider,3-7 days from the concussive injury at the time of enrolment

considered at-risk for protracted recovery based on Immediate Post-concussion Assessment and Cognitive Testing (ImPACT) performance and symptom reporting on the Post-Concussion Symptom Scale (PCSS)

Disqualifiers

acute neurologic deterioration to a Glasgow Coma Scale score less than 13

neurosurgical intervention

abnormal CT scan

concomitant extracranial injury worse than mild

Trial design

Treatments tested in this trial

  • Photobiomodulation therapy (PBMt)
  • Standard of Care

Treatment groups

30 Participants
are divided into 2 treatment groups

Sponsors and collaborators