About this trial
The purpose of this study is to compare effects of Photobiomodulation therapy (PBMt) to standard of care in adolescent athletes at risk for delayed recovery from subacute sports concussion, to substantiate the impact of subacute PBMt over time on functional and structural connectivity of the brain using advanced MRI sequences and to correlate the psychological and behavioral outcomes to neuroimaging findings
Eligibility criteria
Qualifiers
current participants in a school- or club-sponsored sport (contact or non-contact)
access to wireless internet service at home
diagnosis of sports-related concussion (SRC) (according to consensus diagnostic criteria) by a licensed healthcare provider,3-7 days from the concussive injury at the time of enrolment
considered at-risk for protracted recovery based on Immediate Post-concussion Assessment and Cognitive Testing (ImPACT) performance and symptom reporting on the Post-Concussion Symptom Scale (PCSS)
Disqualifiers
acute neurologic deterioration to a Glasgow Coma Scale score less than 13
neurosurgical intervention
abnormal CT scan
concomitant extracranial injury worse than mild
Trial design
Treatments tested in this trial
- Photobiomodulation therapy (PBMt)
- Standard of Care
Treatment groups
Sponsors and collaborators
The University of Texas Health Science Center, Houston
Lead sponsor
TIRR/Mission Connect
Collaborator