The goal of this observational study is to learn about the incidence of Transplant Associated Thrombotich Microangiopathy (TA-TMA), which is a known but underreported complication of Allogeneic Stem Cell Transplant (SCT). The main question it aims to answer is:
What is the incidence of TA-TMA in adults undergoing SCT? How does TA-TMA diagnosis impact survival and other outcomes? Patients undergoing SCT will be eligible for this study, which will consist of collection of biological samples and standard clinical follow up.
Inclusion Criteria
Adult male or female, age ≥18
Undergoing allogeneic SCT at UAB for any indication and any donor source.
BMI > 35[42]
Exclusion Criteria
Any other active malignancy requiring treatment or with expected survival ≤1 year.
Patients with psychiatric illness or social situations that would limit compliance with the study requirements.
Manuel Ricardo Espinoza-Gutarra
Lead sponsor
University of Alabama at Birmingham
Sponsor institution
BMS Foundation
Collaborator
Viracor Eurofins
Collaborator