The objective of this study is to assess the effects of Hass Avocados on glycemic control. The investigators hypothesize that Hass Avocado consumption will reduce fasting blood sugar compared to an isocaloric amount of other fruit during controlled feeding.
Participant reported diagnosis of Type 2 diabetes
HbA1c between 5.7%-11% (inclusive) and / or fasting blood glucose of ≥ 100 mg/dL
BMI 27-50 kg/m2 (inclusive)
Age range - 18 - 65 years (inclusive)
Not willing or unable to consume study foods including avocados
Participation in a weight control program within the past 3 months or weight loss of ≥ 5 kg in the previous 3 months
Taking prescription or OTC weight loss medications within last 4 weeks
History of a surgical procedure for weight loss in last 5 years (e.g. gastroplasty, gastric by-pass, gastrectomy or partial gastrectomy, adjustable banding, gastric sleeve)
Crossover
Avocado
Other interventionThe Hass Avocado group will consume 7 avocados a week (1 / day; \~240 kcals/d).
Other Fruit(s)
Other interventionThe other fruits group will consume fruit(s) matched to the avocado in energy and form (i.e., solid fruit).
Fasting Blood Glucose
the primary outcomes are based on within subject concentration change scores
Fasting Insulin
within subject concentration change scores
Fructosamine
within subject concentration change scores
Glycated Albumin
within subject concentration change scores
Blood Glucose
Continuous Glucose Monitoring
Glucose
Oral Glucose Tolerance Test (OGTT)
Insulin
Oral Glucose Tolerance Test (OGTT)
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Pennington Biomedical Research Center
Lead sponsor
Prachi Singh
Collaborator
Frank L. Greenway
Collaborator
Robbie A. Beyl
Collaborator
