To comprehensively evaluate subclinical organ damage of Chinese adults and its association with future cardiovascular disease and events.
To observe the significance of intervention based on digital health in preventing the onset and/or progression of subclinical organ damage and cardiovascular disease and events.
aged 18 years or older
willing to participate the study and sign informed consent
available for long-term follow-up
severe heart disease (NYHA IV)
stage 4 or 5 CKD
malignant tumors or with life expectancy less than 5 years
stroke within 3 months