Assessment of Eloquent Function in Brain Tumor Patients
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age19+
SponsorUniversity of Nebraska
About this trial
Purpose of the study:
AIM 1: Prospectively collect pre-operative \[functional magnetic resonance imaging (fMRI), diffusion tensor imaging (DTI), magnetoencephalography (MEG)\] and intra-operative mapping data in patients with intra-axial brain tumors to assess how well each modality predicts the location of eloquent brain function. In addition, each modality will be compared with the other.
AIM 2: Assess reorganization of eloquent brain function and plasticity in patients with intra-axial brain tumors. This will be accomplished by prospectively collecting post-operative mapping studies and neuropsychological tests to compare them to prior mapping studies as stated above.
Eligibility criteria
Qualifiers
19 years and older
Brain tumor in or near eloquent brain regions that is appropriate for attempted resection
Appropriate body habitus and mental status/capacity to participate with non-invasive or invasive mapping
Benign or malignant intra-axial brain tumor
Disqualifiers
Any contraindication to MRI (i.e. implanted devices)
Inappropriate body habitus or mental status/capacity to participate with non-invasive or invasive mapping in a safe and reliable manner
Declining to participate
Lacks capacity to understand the study or consent for themselves
Trial design
Treatments tested in this trial
- Brain mapping
Treatment groups
75 Participants
are divided into 1 treatment groupSponsors and collaborators
Source ClinicalTrials.gov