Assessment of Laryngopharyngeal Sensation: Cancer Survivor Cohort

Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-85
SponsorUniversity of California, San Francisco

About this trial

A previous study completed in 2022 (NCT05158179) was conducted using cohorts of healthy controls, and adults with general laryngopharyngeal disorders. This study will expand on the previous research to include a separate cohort of adults being seen in clinic for an existing laryngopharyngeal disorder resulting from previous radiation or other cancer treatments.

Eligibility criteria

Qualifiers

Age <=18 years.

Individuals without a laryngopharyngeal disorder (health controls) or with a laryngopharyngeal disorder. Laryngopharyngeal disorder includes but is not limited to: presbylarynx, aspiration; spasmodic dysphonia; globus pharynges; vocal fold paralysis; iatrogenic injury to the larynx; muscle tension dysphonia; neurogenic dysphagia; laryngeal sensory neuropathy; and laryngopharyngeal disorders resulting from prior radiation therapy in individuals with a history of head and neck cancer who have completed radiation therapy as primary or adjuvant cancer treatment

Ability and willingness to comply with study procedures.

Ability to understand a written informed consent document, and the willingness to sign it.

Disqualifiers

Non-English speaking.

Laryngopharyngeal structures are not accessible on exam.

Known contraindication to any study-related procedure, or history of being unable to tolerate laryngoscopy.

Vocal fold immobility or severe hypomobility on adduction.

Trial design

Treatments tested in this trial

  • Cheung-Bearelly Aesthesiometer
  • Transnasal Laryngoscopy
  • Questionnaires

Treatment groups

40 Participants
are divided into 1 treatment group

Sponsors and collaborators

University of California, San Francisco

Lead sponsor

National Spasmodic Dysphonia Association

Collaborator