About this trial
A previous study completed in 2022 (NCT05158179) was conducted using cohorts of healthy controls, and adults with general laryngopharyngeal disorders. This study will expand on the previous research to include a separate cohort of adults being seen in clinic for an existing laryngopharyngeal disorder resulting from previous radiation or other cancer treatments.
Eligibility criteria
Qualifiers
Age <=18 years.
Individuals without a laryngopharyngeal disorder (health controls) or with a laryngopharyngeal disorder. Laryngopharyngeal disorder includes but is not limited to: presbylarynx, aspiration; spasmodic dysphonia; globus pharynges; vocal fold paralysis; iatrogenic injury to the larynx; muscle tension dysphonia; neurogenic dysphagia; laryngeal sensory neuropathy; and laryngopharyngeal disorders resulting from prior radiation therapy in individuals with a history of head and neck cancer who have completed radiation therapy as primary or adjuvant cancer treatment
Ability and willingness to comply with study procedures.
Ability to understand a written informed consent document, and the willingness to sign it.
Disqualifiers
Non-English speaking.
Laryngopharyngeal structures are not accessible on exam.
Known contraindication to any study-related procedure, or history of being unable to tolerate laryngoscopy.
Vocal fold immobility or severe hypomobility on adduction.
Trial design
Treatments tested in this trial
- Cheung-Bearelly Aesthesiometer
- Transnasal Laryngoscopy
- Questionnaires
Treatment groups
Sponsors and collaborators
University of California, San Francisco
Lead sponsor
National Spasmodic Dysphonia Association
Collaborator