Assessment of Nutrient Absorption in Enterally Fed Post-intensive Care Unit Patients Using Bomb Calorimetry: do the Calories Stick

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorUniversitair Ziekenhuis Brussel

About this trial

This study focuses on understanding how well patients who have recovered from an ICU stay absorb nutrients when receiving enteral (tube) feeding. Proper nutrition is crucial for recovery, but we don't fully understand how efficiently enteral feeding works in ICU survivors. The study will use advanced techniques like bomb calorimetry to measure the energy content of stool, and indirect calorimetry to measure patients' resting energy expenditure (REE). This will help assess the effectiveness of enteral feeding in these patients, providing valuable information about their metabolic needs and nutritional status.

The study will also look into the environmental impact of enteral feeding, particularly food waste. By understanding how much of the nutrition is absorbed versus excreted, the study hopes to suggest more sustainable feeding practices and reduce unnecessary waste in hospitals.

Key Goals:

* Primary Goal: Measure how much energy from enteral feeding is absorbed by patients post-ICU by analyzing their stool and energy expenditure. * Secondary Goal: Assess how enteral feeding can be made more sustainable, with less waste generated from unused nutritional products.

This research will help improve nutritional care for ICU patients, enhance recovery, and potentially lead to more environmentally friendly healthcare practices.

Eligibility criteria

Qualifiers

age of 18 years or older

minimum ICU stay of 7 days

fully dependent on enteral feeding (nasogastric or PEG-tube)

ability of the patient or representative to understand and sign written informed consent in Dutch, French or English

Disqualifiers

known inflammatory bowel disease

known malabsorptive gastrointestinal disease

history of small bowel resection

concomitant use of serotoninergic or sympathomimetic medications (oa. setrone, tryptans, antidepressants, methylphenidate, monoamine oxidase inhibitors, tramadol)

Trial design

Treatments tested in this trial

  • caloric intake measurement
  • stool sample collection
  • energy expenditure measurement

Treatment groups

20 Participants
are divided into 1 treatment group

Sponsors and collaborators

Universitair Ziekenhuis Brussel

Lead sponsor

Société des Produits Nestlé (SPN)

Collaborator