About this trial
The primary objective of this study is the evaluation of the efficacy of the tissue oxygen imager based on PpIX DF in differentiating benign skin growth from non-melanoma skin cancer (NMSC).
Eligibility criteria
Qualifiers
Adults ≥ 18 years of age.
Histologic proof of non-melanoma skin cancer. Patients with different skin tones based on the Fitzpatrick Scale, who present with skin growth or lesions and are scheduled for resection.
As determined by the enrolling physician or study team member, the patient must have the willingness and ability to understand and comply with study procedures.
Women of childbearing potential (WOCBP): Premenopausal females who had at least one menstrual cycle in the past 12-months and capable to become pregnant, must have a negative serum beta-HCG pregnancy test result within seven days prior to start of study.
Disqualifiers
Patients who are <18 years of age
Adults who are unable to provide informed consent.
Known allergy to Ameluz
Photosensitivity or photodermatoses or similar conditions.
Trial design
Treatments tested in this trial
- Ameluz 10% Topical Gel
- Protoporphyrin IX
Treatment groups
Sponsors and collaborators
Dartmouth-Hitchcock Medical Center
Lead sponsor
Dartmouth College
Collaborator