Assessment of Stroke Volume and Cardiac Output in Response to Varying Heart Rates
ConditionVasovagal Syncope
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-70
SponsorUniversity of Calgary
The investigators will seek to determine the effects of different heart rates on both stroke volume and cardiac output using non-invasive hemodynamic assessments. In order to safely manipulate the HR, the investigators will study patients with permanent pacemakers in whom heart rate manipulation can be done in a safe and non-invasive manner.
Age 18-70 years (inclusive)
Implanted permanent pacemaker or implanted defibrillator capable of atrial and ventricular pacing
LV ejection fraction >50%
Unable or unwilling to provide informed consent
Clinical need for a cardiac resynchronization device