Assessment of Stroke Volume and Cardiac Output in Response to Varying Heart Rates

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-70
SponsorUniversity of Calgary

About this trial

The investigators will seek to determine the effects of different heart rates on both stroke volume and cardiac output using non-invasive hemodynamic assessments. In order to safely manipulate the HR, the investigators will study patients with permanent pacemakers in whom heart rate manipulation can be done in a safe and non-invasive manner.

Eligibility criteria

Qualifiers

Age 18-70 years (inclusive)

Implanted permanent pacemaker or implanted defibrillator capable of atrial and ventricular pacing

LV ejection fraction >50%

Disqualifiers

Unable or unwilling to provide informed consent

Clinical need for a cardiac resynchronization device

Trial design

Treatments tested in this trial

  • Pacing

Treatment groups

25 Participants
are divided into 1 treatment group

Sponsors and collaborators