About this trial
To study the effect vitamin D effect on orthodontic tooth movement when used in combination with coticision technique, independent t test or an equivalent non-parametric test will be used for comparison. According to a previous study by (S. T. Varughese, et al. (2019) , "Effect of vitamin D on canine distalization and alveolar bone density using multi-slice spiral CT: a randomized controlled trial
Eligibility criteria
Qualifiers
Orthodontic patients referred for therapeutic extraction of bilateral maxillary first premolars (Angle Class II division 1 cases, with crowding and bimaxillary protrusion).
Fully erupted permanent teeth (except third molar).
Age 13-20 patients.
No previous orthodontic treatment.
Disqualifiers
Patients with impacted canines.
Patients with severe crowding.
Patients with untreated decay or any endodontic lesions.
Patients with thyroid, parathyroid, or renal and liver disease.
Trial design
Treatments tested in this trial
- patients will receive local application of vitamin D3 combined with corticision