Assessment of the Relationship Between Cerebral Blood Flow and Heart Rate
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-70
SponsorUniversity of Calgary
About this trial
The investigators will seek to determine the relationship between heart rate and middle cerebral artery (MCA) cerebral blood flow (CBF), as well as better understand the hemodynamic determinants of MCA CBF velocity. In order to manipulate heart rate, the investigators will recruit patients already scheduled for clinically indicated elective electrophysiological studies, where temporary pacing catheters placed in the right atrium can be used to artificially pace the heart at controlled rates. MCA CBF will be measured by transcranial Doppler ultrasound.
Eligibility criteria
Qualifiers
Male or female
Age 18-70 years, inclusive
Scheduled for clinically indicated elective electrophysiological studies where temporary pacing catheters are being placed in the right atrium
Left ventricular ejection fraction ≥50%
Disqualifiers
Unable or unwilling to provide informed consent
Other factors which in the investigator's opinion would prevent the participant from completing the protocol
Trial design
Treatments tested in this trial
- Electrophysiological Pacing
Treatment groups
20 Participants
are divided into 1 treatment groupSponsors and collaborators
Source ClinicalTrials.gov