Patients evaluated at Penn Presbyterian Medical Center for traumatic brain injury (TBI), who sign the informed consent, will undergo assessment of electrophysiologic potentials evoked by transcranial magnetic stimulation (TMS), using the Delphi-MD device (QuantalX Neuroscience Ltd., Saba Israel).
Age 18 years and older
Evidence of mechanical energy impacting the head or inertial forces affecting the head
Trauma-related abnormality on CT scan on admission
If CT normal, documented/verified TBI based on evidence of either loss of consciousness, post-traumatic amnesia, confusion, or post-traumatic symptoms.
History of disabling pre-existing neurologic disease (Such as epilepsy, brain tumors, meningitis, cerebral palsy, encephalitis, brain abscesses, vascular malformations, cerebrovascular disease, Alzheimer's disease, multiple sclerosis, or HIV-encephalitis)
History of premorbid disabling condition that interfere with outcome assessments
Bilaterally absent pupillary responses
Penetrating traumatic brain injury
Ramon Diaz-Arrastia
Lead sponsor
University of Pennsylvania
Sponsor institution
QuantalX Neuroscience
Collaborator