Assessment the Cancer Risk of Indeterminate Thyroid Nodules Through Integration of Clinical, Ultrasonographic and Multiomic Features

Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorUniversity of Cagliari

About this trial

Indeterminate thyroid nodules have a mild risk of malignancy (15-30%). The aim of our study is to individuate new biomarkers of thyroid carcinoma through multiomic analyses of blood samples and of specimen samples of patients with indeterminate thyroid nodules.

Eligibility criteria

Qualifiers

Patients with indeterminate thyroid nodules (Class III and Class IV according to Bethesda Classification of thyroid nodules)

Disqualifiers

Patients with concomitant thyroid nodules of Bethesda Class V or Class VI

Patients with preoperative diagnosis of lymph node metastases of central or lateral neck compartment

Patients with distant metastases

Trial design

Treatments tested in this trial

  • Multiomic analyses of blood and surgical specimens

Treatment groups

256 Participants
are divided into 2 treatment groups

Sponsors and collaborators

University of Cagliari

Lead sponsor

Prof. Pietro Giorgio Calò

Collaborator

Dott. Gian Luigi Canu

Collaborator