The purpose of this research study is to study the effects of endurance exercise training on adipose (fat) tissue quality and insulin sensitivity in men and women.
Men and pre-menopausal women;
18-45 years of age;
BMI 30.0-40.0 kg/m2;
For women, if not using pharmaceutical (hormonal) contraception (i.e. birth control pills, vaginal ring, injections, or implant), must agree to use either a double barrier method as a form of birth control to prevent pregnancy (i.e. male condom with spermicide, with or without cervical cap or diaphragm); use implants or intrauterine contraceptive devices; have a tubal ligation (surgically sterile); practice abstinence; or be in an established relationship with a vasectomized or same sex partner during the entire duration of the study;
Self-reported unstable body weight in the last 3 months (> ±5%);
Significant changes in the quality of the diet or the level of physical activity within the last 3 months;
Weight >396 lb (180 kg);
Diagnosis of Type 1 or Type 2 diabetes mellitus;
AdventHealth Translational Research Institute
Lead sponsor
Pennington Biomedical Research Center
Collaborator