Association Between Genetic Polymorphisms and Type 2 Asthma in Children
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age3-14
SponsorGuangzhou Institute of Respiratory Disease
About this trial
To further understand the role of gene single nucleotide polymorphism (SNP) in the occurrence of type 2 inflammation-related asthma in children by analyzing the gene single nucleotide polymorphism (SNP), lung function and type 2 inflammation indicators of children diagnosed with asthma in outpatient and inpatient. To provide a theoretical basis for the study of personalized treatment and prevention strategies for asthma.
Eligibility criteria
Qualifiers
All children with asthma diagnosis accord with the GINA in 2023 edition;
Other diseases that could cause wheezing and cough were excluded, such as acute laryngitis, diphtheria, congenital airway abnormalities, and tracheal foreign bodies;
In front of the hospital 2 weeks without antibiotics, systemic hormone medication history;
There were no other complications, such as congenital heart disease, pneumonia, gastroesophageal reflux disease, muscle dysplasia, etc.
Disqualifiers
Children who had taken immunosuppressants, antibiotics and other drugs for a long time before admission;
Children with primary immunodeficiency disease;
The children and their families failed to cooperate or refused the experimental observation.
Trial design
Treatments tested in this trial
- Not listed
Trial groups
300 Participants
are grouped into 2 trial groupsSponsors and collaborators
Source ClinicalTrials.gov