Association Between Tinnitus and Hearing Loss in Locally Advanced Head and Neck Cancer Treated by Radiotherapy Alone or With Chemotherapy: a Prospective and Multicenter Study

Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorAssistance Publique - Hôpitaux de Paris

About this trial

The aim of the AURACCO study is to evaluate the association between the onset of tinnitus and hearing loss in patients with locally advanced head and neck cancer treated by concomitant chemoradiotherapy or exclusive radiotherapy

Eligibility criteria

Qualifiers

Patient with locally advanced or post-operative ENT cancer with high risk of recurrence

Patient ≥ 18 years

Absence of prior chemotherapy or radiotherapy

Patient eligible for chemotherapy with cisplatin according to the standard regimen: radiotherapy delivering 60-70 Gy in 30-35 fractions spread over 6 to 7 weeks associated with chemotherapy with cisplatin 100 mg/m2 every 3 weeks (i.e. at week 1, 4 and 7)

Disqualifiers

Tinnitus grade ≥ 2 according to the SOMA-LENT scale

Patient fitted for hearing disorders

Significant cognitive disorders that may compromise the performance of the various assessments

Patients treated with weekly cisplatin

Trial design

Treatments tested in this trial

  • Not listed

Trial groups

140 Participants
are grouped into 2 trial groups