Associations Between Dietary Patterns, LDL Aggregation, and Cardiometabolic Health: A Cross-sectional Analysis.

Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age25-60
SponsorLiverpool John Moores University

About this trial

This study aims to investigate the extent to which vegan or plant-based, omnivorous, and carnivore dietary patterns affect LDL aggregation susceptibility (the affinity for LDL cholesterol particles to clump together in the blood), which may promote plaque build-up in arteries. Using a cross-sectional mixed-methods design, the study will measure LDL aggregation, blood lipids, and other metabolic biomarkers in individuals following these diets, and combine these data with dietary and behavioural information to examine links with cardiovascular and metabolic health.

Eligibility criteria

Qualifiers

Adults aged 25-60 years.

BMI range (18.5-29.9 kg/m²).

Following one of the specified dietary patterns (vegan/plant-based, carnivore, or omnivorous) for a minimum of 6 months.

Self-identified as health-focused (i.e., intentionally following the diet for perceived health benefits).

Disqualifiers

BMI outside the stated range (<18.5 or ≥30 kg/m²).

Use of lipid-lowering medications or supplements that may interfere with LDL levels.

Pregnancy or breastfeeding.

Any significant deviation from the specified diet within the last month.

Trial design

Treatments tested in this trial

  • Not listed

Trial groups

90 Participants
are grouped into 3 trial groups