Atrial Fibrosis in Obstructive Sleep Apnea Patients: A Pilot Study
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-75
SponsorTulane University
About this trial
The investigators hypothesize that Obstructive Sleep Apnea (OSA) is an independent risk factor for atrial fibrosis development. The investigators aim to prove the presence of atrial fibrosis on Delayed Enhancement Magnetic Resonance Imaging (DE-MRI) in OSA patients without atrial fibrillation (AF).
Eligibility criteria
Qualifiers
In this group, patients with AF and OSA who already have done MRI might be included.
Disqualifiers
History of chronic heart failure (LVEF < 50%), AF, myocardial infarction, valvular disease.
Prior cardiac or chest surgery.
Other advanced pulmonary disease (severe Chronic Obstructive Pulmonary Disease (COPD) or asthma, pulmonary hypertension) or central sleep apnea.
Contraindications to DE-MRI (e.g. allergy to gadolinium, pacemakers, defibrillators (ICD's), other devices/implants contraindicated for MRI, glomerular filtration rate <30 ml/min, etc.).
Trial design
Treatments tested in this trial
- Delayed enhancement magnetic resonance imaging (DE-MRI)
Treatment groups
60 Participants
are divided into 6 treatment groups6
Treatment groupsSee each treatment group below.
Sponsors and collaborators
Source ClinicalTrials.gov