Atrophic Age-related Macular Degeneration Treated With Intravitreal Injections of Umbilical Cord Blood Platelet-rich Plasma

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age65+
SponsorFondazione Policlinico Universitario Agostino Gemelli IRCCS

About this trial

The objective of the study will be to evaluate the efficacy of intravitreal injections of Umbilical Cord Blood Platelet-rich Plasma (CB-PRP) in order to reduce or stabilize the atrophic progression in dry Age-related Macular Degeneration (AMD)

Eligibility criteria

Qualifiers

Age ≥65 years

Bilateral dry-AMD

ETDRS-corrected visual acuity between (or equal to) 1/10 and 4/10

No concomitant ocular pathology (e.g., Glaucoma, amblyopia) or systemic pathology that would result in a BIAS for primary goal assessment

Disqualifiers

Age < 65 years

Pregnancy

Previous inflammatory/infectious events involving the eyes

Eye trauma, diabetes, or disease potentially damaging to the visual system, even in the absence of impairment at the time of intake

Trial design

Treatments tested in this trial

  • Intravitreal injection of CB-PRP

Treatment groups

36 Participants
are divided into 3 treatment groups