Auditory EEG and Behavioral Assessments in Individuals With Rett Syndrome
ConditionRett Syndrome
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age2+
SponsorUniversity of Rochester
About this trial
This observational research study is designed to learn more about how the brain processes sound in individuals with Rett syndrome. Participants will complete a noninvasive electroencephalogram (EEG) recording while listening to simple sounds through headphones. In addition, parents or caregivers will complete questionnaires and an interview about the participant's symptoms, communication abilities, daily functioning and overall health. The information collected from this study may help researchers better understand brain activity patterns and clinical features associated with Rett syndrome and support future research efforts.
Eligibility criteria
Qualifiers
Have a clinical diagnosis of classic Rett syndrome
Have a pathogenic MECP2 genetic variant confirmed via genetic testing
Are past the clinical regression stage
Are within the eligible age range for the study (2 years or older)
Disqualifiers
Experiences hearing impairment or hearing loss
Presence of medical conditions that would prevent safe participation in EEG recording
Inability to tolerate EEG procedures
Any condition that in the opinion of the investigator would interfere with study participation or data quality
Trial design
Treatments tested in this trial
- Electroencephalogram (EEG) Recording
Treatment groups
60 Participants
are divided into 2 treatment groupsSponsors and collaborators
Source ClinicalTrials.gov