AusCADASIL: An Australian Cohort of CADASIL

ConditionCadasil
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorPerminder Sachdev

About this trial

The aim of this project is to establish an Australian cohort of patients diagnosed with Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy (CADASIL). This study will examine the clinical features and longitudinal course of CADASIL. Outcome measures include neuropsychological profile, neuroimaging, genetics, blood biomarkers, and retinal imaging.

Eligibility criteria

Qualifiers

Adults ≥18 years old

Ability to provide written informed consent

A large-print version is available for individuals with visual impairment

An easy-to-read version is available for individuals with cognitive difficulties who may require extra support

Disqualifiers

None

Trial design

Treatments tested in this trial

  • Not listed

Trial groups

300 Participants
are grouped into 2 trial groups

Sponsors and collaborators

Perminder Sachdev

Lead sponsor

The University of New South Wales

Sponsor institution

Prince of Wales Hospital, Sydney

Collaborator

John Hunter Hospital

Collaborator

St Vincent's Hospital - Sydney, Australia

Collaborator

Royal Brisbane and Women's Hospital

Collaborator

Melbourne Health

Collaborator

The University of Queensland

Collaborator