Autoimmunity After Checkpoint Blockade

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorAbramson Cancer Center at Penn Medicine

About this trial

The purpose of this study is to better understand how the treatment of cancer with immune checkpoint inhibitors (ICI) leads to the development of autoimmunity. Specifically, we wish to understand the genetics and immune system features that cause a subset of cancer patients treated with checkpoint inhibitor therapy to develop an immune-related adverse event (irAE).

Eligibility criteria

Qualifiers

A diagnosis of cancer and prescription for a checkpoint inhibitor

Disqualifiers

Any subjects not willing or able to give consent

Children under the age of 18

A history of transplant

Trial design

Treatments tested in this trial

  • Not listed

Trial groups

600 Participants
are grouped into 1 trial group